STREPTOLYSIN PRODUCTION IN CARBOHYDRATE MEDIA

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Streptolysin Production in Carbohydrate Media

It is evident that there are numerous interacting factors which affect streptolysin in the presence of fermented sugars. The principal action is the change in the metabolism of the streptococcus by which more carbohydrate and less protein is utilized; although the growth is much increased there is proportionately less hemolysin. The acid developed in these cultures not only lessens the vitality...

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Group A streptococcus (GAS) is an important human pathogen that causes pharyngitis and invasive infections, including necrotizing fasciitis. Streptolysin S (SLS) is the cytolytic factor that creates the zone of beta-hemolysis surrounding GAS colonies grown on blood agar. We recently reported the discovery of a potential genetic determinant involved in SLS production, sagA, encoding a small pept...

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The production, concentration, and partial characterization of streptolysin O.

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Effects of polynucleotides on production and activity of streptolysin S.

Activity of various natural and synthetic polynucleotides as a carrier for streptolysin S was tested in a resting cell system. As the carrier, intact molecules of MS2 RNA, E coli tRNA or rat liver RNA were almost inactive, whereas RNase I core of these RNAs, especially the core fractions eluted from DEAE-cellulose column at higher NaCl concentrations, effectively induced production of the extra...

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ژورنال

عنوان ژورنال: Journal of Experimental Medicine

سال: 1919

ISSN: 1540-9538,0022-1007

DOI: 10.1084/jem.30.6.539